Magnesium Glycinate vs Threonate for Sleep

Detailed Head-to-Head Comparison

Both forms of magnesium are excellent for sleep, but they work differently. Glycinate provides systemic relaxation and is more affordable, while Threonate specifically crosses the blood-brain barrier for cognitive benefits.

The Verdict

Choose Magnesium Glycinate for general sleep support and muscle relaxation. Choose Threonate if you also want cognitive benefits and can afford the higher price.

Feature Comparison

FeatureMagnesium GlycinateMagnesium Threonate
Sleep QualityExcellentExcellent
Crosses Blood-Brain BarrierLimitedYes
Muscle RelaxationExcellentGood
Cognitive BenefitsLimitedYes (studied)
PriceAffordableExpensive
Elemental Mg per DoseHigherLower
Research for SleepGoodGood
GI ToleranceExcellentExcellent

Magnesium Glycinate

Pros

  • Excellent for sleep and relaxation
  • Glycine adds calming benefits
  • Very affordable
  • Well-absorbed without GI issues
  • Good for muscle cramps/restless legs

Cons

  • Limited brain penetration
  • Less research on cognitive effects
  • May need to pair with other nootropics

Magnesium Threonate

Pros

  • Specifically designed to cross blood-brain barrier
  • May improve memory and cognition
  • Studied for brain health
  • Well-tolerated
  • Patented Magtein form

Cons

  • Significantly more expensive
  • Lower elemental magnesium content
  • Need more capsules per dose

Who Should Choose What

Choose Magnesium Glycinate if:

Most people who want better sleep, muscle relaxation, and general magnesium supplementation

Choose Magnesium Threonate if:

Those who want cognitive benefits alongside sleep improvement and don't mind paying more

Pricing Comparison

Magnesium Glycinate

$15-25 for 2-month supply

Magnesium Threonate

$40-60 for 1-month supply

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